Thermo Fisher Scientific ELL Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Positive test controls include: Mouse testis, Mouse liver.
The target is usually found in the following locations: Cajal body, Nucleus, Nucleus speckle.

Immunogen sequence:
PAVNGKLGVP NGREALLPTP GPPASTDTLS SSTHLPPRLE PPRAHDPLAD VSNDLGHSGR DCEHGEAAAP APTVRLGLPL LTDCAQPSRP HGSPSRSKPK K

Target Information

Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription.
ELL also plays an early role before its assembly into the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site.
Required to stabilize the pre-initiation complex and early elongation.
[UniProt]

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.