Thermo Fisher Scientific Human KIT [V560G], GST Tag Recombinant Protein

Thermo Fisher Scientific Human KIT [V560G], GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Publications

• [References not provided]

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
• For larger sizes, aliquots may be prepared to reduce freeze/thaw cycles (do not prepare aliquots below 20 µL).
• Do not store kinase diluted.
• Guaranteed for 6 months from date of purchase if properly stored at -80°C.

This KIT V560G recombinant human protein (544-end) was expressed in insect cells.
Available in multiple pack sizes for convenient use and validated for use with the Z'-LYTE™ assay.

Also offered through the SelectScreen™ Kinase Profiling Service.

Protein Form: Recombinant, Active, Catalytic, Mutant
Gene Accession Number: NP_000213.1

Target Information

KIT receptor tyrosine kinase is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor).
KIT regulates growth and activation of various hemopoietic and non-hemopoietic cells.
Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism.
Deregulation by the activation loop mutation D816V is a therapeutic target for neoplastic mast cell growth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.