Thermo Fisher Scientific PIGF Polyclonal Antibody
Rabbit polyclonal antibody against human PIGF. Validated for Western Blot at 1:1,000 dilution. Predicted cross-reactivity with mouse samples. Supplied as liquid, 1 mg/mL concentration. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PIGF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691885 |
Product Specific Information
Predicted to react with mouse samples.
Target Information
Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs are essential for the biosynthesis of the glycosylphosphatidylinositol (GPI) anchor. Some PIG proteins are components of the GPI transamidase complex and play a role in recognizing either the GPI attachment signal or the lipid portion of GPI. Others belong to the glycosyltransferase complex, transferring N-acetylglucosamine (GlcNAc) to phosphatidylinositol (PI).
PIG-F functions as an auxiliary subunit of ethanolamine phosphate (EtNP) transferases, associating with PIG-O to ensure its expression and stability. Together, they catalyze the transfer of EtNP to the third mannose (Man-3) of GPI. Mutations in the PIG-F gene may block EtNP addition to Man-3, leading to the absence of GPI-anchored proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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