Thermo Fisher Scientific ALDH5A1 Polyclonal Antibody
ALDH5A1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 면역세포염색에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ALDH5A1 (Accession P51649), corresponding to amino acid residues A355–T405 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899475 |
Product Specific Information
This antibody detects endogenous levels of total ALDH5A1.
Target Information
Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. Deficiency of this enzyme, known as 4-hydroxybutyricaciduria, causes a disorder of the neurotransmitter 4-aminobutyric acid (GABA), leading to static encephalopathy, developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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