Thermo Fisher Scientific Claudin 6 Monoclonal Antibody (342927)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

8-25 µg/mL

-

Flow Cytometry (Flow)

0.25 µg per million cells

-

Product Specifications

Species Reactivity

Human

Published species

Amphibian

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

342927

Immunogen

NS0 mouse myeloma cell line transfected with human Claudin-6 Met1-Val220 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Claudin 6,uniProtId:P56747-1,ncbiNodeId:9606,antigenRange:1-220,antigenLength:220,antigenImageFileName:MA5-24076_Claudin_6_P56747-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24076_Claudin_6_P56747-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608443

Product Specific Information

This antibody stains human Claudin-6 transfected cells but not irrelevant transfectants.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.