Thermo Fisher Scientific PMP70 Recombinant Rabbit Monoclonal Antibody (ARC2131)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

-

Immunocytochemistry (ICC/IF)

1:200-1:800

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC2131

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 560-659 of human PMP70/ABCD3 (P28288) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PMP70,uniProtId:P28288-1,ncbiNodeId:9606,antigenRange:560-659,antigenLength:659,antigenImageFileName:MA5-38109_PMP70_P28288-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38109_PMP70_P28288-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898027

Product Specific Information

Positive Samples: HepG2, A-549, Mouse liver, Mouse kidney, Rat liver

Immunogen sequence: GWDSVQDWMD VLSGGEKQRM AMARLFYHKP QFAILDECTS AVSVDVEGYI YSHCRKVGIT LFTVSHRKSL WKHHEYYLHM DGRGNYEFKQ ITEDTVEFGS

Target Information

Peroxisomes are single membrane organelles which are involved with many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including, phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via beta-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum` disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal beta-oxidation enzymes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.