Thermo Fisher Scientific PMP70 Recombinant Rabbit Monoclonal Antibody (ARC2131)
PMP70 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, ELISA 등에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 고순도의 Affinity chromatography 정제 항체입니다. -20°C 보관, 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:800 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2131 |
| Immunogen | Synthetic peptide corresponding to amino acids 560–659 of human PMP70/ABCD3 (UniProt ID: P28288) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898027 |
Product Specific Information
- Positive Samples: HepG2, A-549, Mouse liver, Mouse kidney, Rat liver
- Immunogen Sequence:
GWDSVQDWMD VLSGGEKQRM AMARLFYHKP QFAILDECTS AVSVDVEGYI YSHCRKVGIT LFTVSHRKSL WKHHEYYLHM DGRGNYEFKQ ITEDTVEFGS
Target Information
Peroxisomes are single-membrane organelles involved in various biochemical pathways and are present in nearly all eukaryotic cells. They play key roles in detoxifying compounds such as phenols, alcohols, and aldehydes, as well as in long-chain fatty acid metabolism via beta-oxidation. Dysfunction of peroxisomes can lead to disorders such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum disease.
Peroxisomal membrane protein 70 (PMP70) is a major integral membrane protein of the peroxisome, induced by hypolipidemic agents and associated with peroxisome proliferation and activation of beta-oxidation enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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