
Thermo Fisher Scientific OCT1 (POU2F1) Polyclonal Antibody
OCT1 (POU2F1) 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. 인간 및 랫트 반응성을 가지며, 고순도 항원 친화 크로마토그래피로 정제되어 연구용으로 안정적입니다.
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Thermo Fisher Scientific OCT1 (POU2F1) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 442–755 of Human OCT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545685 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2
- Predicted reactivity: Mouse (89%), Rat (94%), Xenopus laevis (81%), Pig (97%), Chicken (94%), Chimpanzee (99%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates promoters of genes such as small nuclear RNAs (snRNA), histone H2B, and immunoglobulins. It modulates transcriptional transactivation by NR3C1, AR, and PGR. During human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with viral transactivator VP16 and HCFC1, enabling transcription of viral immediate early genes.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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