Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI3E2), TrueMAB
인간 NKX2-1 단백질을 인식하는 mouse monoclonal antibody로, Western blot 및 IHC(P)에서 검증됨. 무보존제, 동결건조 형태로 제공되며 1 mg/mL 농도. 연구용으로 사용되며 thyroid-specific transcription factor 분석에 적합.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E2 |
| Immunogen | Full length human recombinant protein of human NKX2-1 (NP_003308) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a thyroid-specific transcription factor that binds to the thyroglobulin promoter and regulates thyroid-specific gene expression. It also influences genes involved in morphogenesis.
Mutations or deletions are linked to benign hereditary chorea, congenital hypothyroidism, neonatal respiratory distress, and possibly thyroid cancer. Multiple transcript variants exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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