Thermo Fisher Scientific CaV1.1 Polyclonal Antibody
CaV1.1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인체 반응성을 가지며 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고품질 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CACNA1S. Recombinant protein control fragment (Product #RP-99774). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791085 |
Product Specific Information
Immunogen sequence:
ESPVFLEDFP QDPRTNPLAR ANTNNANANV AYGNSNHSNS HVFSSVHYER EFPEETETPA TRGRALGQPC RVLGPHSKPC VE
Target Information
Voltage-sensitive calcium channels mediate the entry of calcium into many types of excitable cells and play a key role in neurotransmitter release and excitation-contraction (E-C) coupling.
The 1,4-dihydropyridines (DHPs) are synthetic organic compounds used to identify L-type calcium channels found in muscle, neuronal, and neuroendocrine cells.
The DHP receptor, part of the L-type calcium channel complex, acts as the voltage sensor in E-C coupling.
It consists of at least four subunits:
- Alpha-1 subunit: Contains the DHP binding site and shows high homology to voltage-gated sodium channels.
- Alpha-2 subunit: Large glycoprotein found in skeletal, cardiac, and brain tissues.
- Beta and Gamma subunits: Co-purify with the DHP receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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