Thermo Fisher Scientific ME2 Polyclonal Antibody
Human ME2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, IHC, ICC 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ME2. Recombinant protein control fragment (Product #RP-88955). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643834 |
Product Specific Information
Immunogen sequence:
DGRVFTPGQG NNVYIFPGVA LAVILCNTRH ISDSVFLEAA KALTSQLTDE ELAQGRLYPP LANIQEVSIN IAIKVTEYLY ANKMAFRYPE PEDKAKYVKE RTWRSEYDSL LPDVYEWPES ASSPPV
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 87%
Target Information
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein that catalyzes the oxidative decarboxylation of malate to pyruvate. It was previously weakly linked to Friedreich ataxia, which is now known to result from a mutation in a different gene. Certain single-nucleotide polymorphism haplotypes of this gene may increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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