Thermo Fisher Scientific PABP Monoclonal Antibody (10E10)
PABP 단백질을 검출하기 위한 Thermo Fisher Scientific의 단클론 항체(10E10). Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합. Human, Chicken, Rabbit, Xenopus 시료 반응. 단백질 A 정제, PBS 버퍼, 4°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Rabbit, Xenopus |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10E10 |
| Immunogen | Recombinant PABP (Human) expressed from its 1.85 kbp cDNA, NcoI to SspI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2156879 |
Product Specific Information
MA1-34079 detects PABP from human, chicken, rabbit, and Xenopus laevis samples. Does not react with Drosophila melanogaster or mouse samples.
Target Information
The poly(A)-binding protein (PABP), which is found complexed to the 3′ poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation.
In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least three functional proteins:
- PABP1 (PABPC1)
- Inducible PABP (iPABP or PABPC4)
- PABP3 (PABPC3)
In addition, there are at least four pseudogenes: PABPCP1 to PABPCP4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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