Thermo Fisher Scientific Ankyrin B Polyclonal Antibody
Ankyrin B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등에 사용 가능. Human 반응성, 항원 친화 크로마토그래피 정제, 액상 형태로 4°C 또는 -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANK2. Recombinant protein control fragment (Product #RP-102423). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789485 |
Product Specific Information
Immunogen sequence:
ERLAYIADHL GFSWTELARE LDFTEEQIHQ IRIENPNSLQ DQSHALLKYW LERDGKHATD TNLVECLTKI NRMDIVHLME TNTEPLQERI SHSYAEIEQT ITLDHSEGFS VLQEELCTAQ HKQKEEQAVS KESETC
Target Information
This gene encodes a member of the ankyrin family of proteins that link integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in cell motility, activation, proliferation, contact, and maintenance of specialized membrane domains. Most ankyrins consist of three structural domains:
- Amino-terminal domain with multiple ankyrin repeats
- Central region with a conserved spectrin binding domain
- Carboxy-terminal regulatory domain (least conserved and variable)
The encoded protein is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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