Thermo Fisher Scientific CD20 (MS4A1) Monoclonal Antibody (OTI11F7), TrueMAB
Human CD20 (MS4A1) 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P)에서 검증됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. B세포 표면 CD20 연구용으로 적합하며, -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11F7 |
| Immunogen | Full length human recombinant protein of human MS4A1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
CD20 is a non-glycosylated surface phosphoprotein with a molecular weight of 33–37 kDa depending on phosphorylation. It is expressed on mature and most malignant B cells, a subpopulation of T lymphocytes, and follicular dendritic cells. CD20 regulates calcium conductance, cell cycle progression, and B-cell proliferation. It associates with lipid rafts and plays a role in BCR aggregation and signaling. CD20 is a key target for antibody-mediated B-cell depletion therapies, remaining on the cell surface after antibody treatment. Dysfunction of CD20 is associated with MS4A1-related common variable immune deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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