Thermo Fisher Scientific DAND5 Monoclonal Antibody (OTI3A3), TrueMAB

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. BMP antagonists contain cystine knots and typically form homo- and heterodimers.
The CAN (cerberus and dan) subfamily, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring.
The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins.
As an antagonist of BMP, this gene may regulate organogenesis, body patterning, and tissue differentiation.
In mouse, this protein binds Nodal and inhibits the Nodal signaling pathway that patterns left/right body asymmetry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.