Thermo Fisher Scientific PTPN7 Monoclonal Antibody (OTI3B10), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
PTPN7 is preferentially expressed in hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells. Its noncatalytic N-terminus interacts with MAP kinases to suppress their activity and is involved in T cell antigen receptor signaling by dephosphorylating molecules in the MAP kinase pathway.
Two alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.