Thermo Fisher Scientific LZTR1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LZTR1. Recombinant protein control fragment (Product #RP-104039). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LZTR1,uniProtId:Q8N653-1,ncbiNodeId:9606,antigenRange:180-259,antigenLength:840,antigenImageFileName:PA5-64381_LZTR1_Q8N653-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64381_LZTR1_Q8N653-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643653

Product Specific Information

Immunogen sequence: ATVYSDKLWI FAGYDGNARL NDMWTIGLQD RELTCWEEVA QSGEIPPSCC NFPVAVCRDK MFVFSGQSGA KITNNLFQFE

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.