
Thermo Fisher Scientific LZTR1 Polyclonal Antibody
Human LZTR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Thermo Fisher Scientific LZTR1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LZTR1. Recombinant protein control fragment (Product #RP-104039). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643653 |
Product Specific Information
Immunogen sequence:
ATVYSDKLWI FAGYDGNARL NDMWTIGLQD RELTCWEEVA QSGEIPPSCC NFPVAVCRDK MFVFSGQSGA KITNNLFQFE
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family. The encoded protein localizes exclusively to the Golgi network, where it may help stabilize the Golgi complex.
Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities, and facial dysmorphism.
LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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