Thermo Fisher Scientific KEAP1 Polyclonal Antibody
Human KEAP1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% 글리세롤 완충액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KEAP1. Recombinant protein control fragment (Product #RP-102475) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789361 |
Product Specific Information
Immunogen sequence:
MYASTECKAE VTPSQHGNRT FSYTLEDHTK QAFGIMNELR LSQQLCDVTL
QVKYQDAPAA QFMAHKVVLA SSSPVFKAMF TNGLREQGME VVSIEGIHPK VMTarget Information
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain.
Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner.
The dissociation of these proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus, resulting in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.
Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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