Thermo Fisher Scientific Centrin 3 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human Centrin 3. Validated for ICC/IF applications. Supplied as a liquid, unconjugated form with 0.5 mg/mL concentration. High specificity and sequence identity with mouse and rat orthologs. For research use only.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Centrin 3. Recombinant protein control fragment (Product #RP-107281) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662060 |
Product Specific Information
- Immunogen sequence: MSLALRSELVV DKTKRKKRRE LSEEQ
- Highest antigen sequence identity: Mouse 96%, Rat 96%
Target Information
The protein encoded by this gene contains four EF-hand calcium binding domains and belongs to the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a key role in centrosome duplication and separation. Multiple human and mammalian forms similar to yeast centrin have been identified, some associated with centrosome fractions. This protein is one of the most abundant centrins associated with centrosomes, suggesting a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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