Thermo Fisher Scientific NKCC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NKCC1 단백질. 면역세포화학(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 완충액(40% glycerol) 보존, 4°C 또는 -20°C에서 보관. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NKCC1. Recombinant protein control fragment (Product #RP-107279) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662988 |
Product Specific Information
Immunogen sequence:
QCLVMTGAPNS RPALLHLVHD FTKNVGLMIC GHVHMGPRRQ AMKEMSIDQA KYQRWLI
Highest antigen sequence identity to orthologs:
- Mouse: 97%
- Rat: 98%
Target Information
NKCC1 mediates sodium and chloride transport and reabsorption. It is a membrane protein essential for maintaining ionic balance and cell volume. NKCC1 functions as an electrically silent transporter system and is phosphorylated in response to DNA damage.
Three transcript variants encoding two different isoforms have been identified for NKCC1.
Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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