Thermo Fisher Scientific SLC39A4 Polyclonal Antibody
인체 SLC39A4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 최적화된 고순도 항체로 항원 친화 크로마토그래피로 정제됨. Zinc transporter ZIP4 연구 및 암 관련 기전 분석에 적합.
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Thermo Fisher Scientific SLC39A4 Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human SLC39A4 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.32 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736614 |
Product Specific Information
- Positive Control: SLC39A4-transfected 293T cells
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The zinc transporter ZIP4 (SLC39A4) is a member of a family of divalent ion transporters. Zinc is essential for cellular growth, development, and differentiation. ZIP4 was identified as a zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in dietary zinc absorption.
Aberrant expression of ZIP4 has been associated with cancer progression, particularly pancreatic cancer. ZIP4 activation has also been observed in hepatocellular carcinomas, where it represses apoptosis, enhances cell cycle progression, and increases migration, suggesting that ZIP4 may play roles in multiple cancer types.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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