Thermo Fisher Scientific ACVR1 Monoclonal Antibody (2C1E8)
인간 ACVR1 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot, Flow cytometry, ELISA에 적합합니다. 단백질 G 정제, 액상 형태, PBS buffer 및 sodium azide 함유. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific ACVR1 Monoclonal Antibody (2C1E8)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C1E8 |
| Immunogen | Purified recombinant fragment of human ACVR1 (aa: 21–120) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898352 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.
ACVR1 signals a specific transcriptional response in concert with activin type II receptors.
Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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