Thermo Fisher Scientific J Chain Monoclonal Antibody (OTI3H7)
J Chain 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI3H7). Western blot 및 IHC(P) 검증 완료. Human 시료 반응성. Affinity 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H7 |
| Immunogen | Full length human recombinant protein of IGJ produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724538 |
Target Information
J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins.
J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells.
J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node.
B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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