Thermo Fisher Scientific ERCC1 Polyclonal Antibody
ERCC1 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 고순도의 액상 형태로 제공됩니다. DNA 복구 관련 연구용으로 적합합니다.
- 카탈로그번호
- PA518837
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DPGKDKEGVPQPS) corresponding to the N-terminus amino acids of ERCC1 (aa 2–15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986315 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. It functions with SLX4 in the first step of interstrand cross-link (ICL) repair and participates in processing anaphase bridge-generating DNA structures that can lead to cytokinesis failure. ERCC1 also contributes to homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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