Thermo Fisher Scientific SON Polyclonal Antibody
SON 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. 연구용으로 HBV 관련 유전자 조절 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SON (Accession P18583), corresponding to amino acid residues K1804–S1854 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900581 |
Product Specific Information
Antibody detects endogenous levels of total SON.
Target Information
The protein encoded by this gene binds to a specific DNA sequence upstream of the regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions.
The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing.
Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined.
(Information provided by RefSeq.)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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