Thermo Fisher Scientific EDG4 Polyclonal Antibody
Rabbit polyclonal antibody against human EDG4 (LPAR2) for IHC-P applications. Detects endogenous total LPAR2/EDG4 protein. Purified by antigen affinity chromatography, supplied in PBS with 40% glycerol. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC-P): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human lysophosphatidic acid receptor 2 (LPAR2/EDG4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636039 |
Product Specific Information
This antibody detects endogenous levels of total LPAR2 / EDG4 protein.
Target Information
Edg4 (also known as LPAR2) is a lysophospholipid/lysosphingolipid receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may regulate interleukin-2 secretion. Expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis, as well as in various cancer cell lines including brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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