
Thermo Fisher Scientific MIOS Polyclonal Antibody
Rabbit polyclonal antibody against human MIOS protein. Validated for WB and IP applications. Unconjugated, liquid form with 1 mg/mL concentration. Recommended storage at 4°C and 1-year shelf life. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 825 to 875 of human Missing Oocyte, Meiosis Regulator, Homolog (MIOS) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
As a component of the GATOR subcomplex GATOR2, MIOS functions within the amino acid-sensing branch of the TORC1 signaling pathway. It indirectly activates mTORC1 and the TORC1 signaling pathway through inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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