Thermo Fisher Scientific MIOS Polyclonal Antibody
MIOS 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, Human과 Mouse 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 825 to 875 of human Missing Oocyte, Meiosis Regulator, Homolog |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
As a component of the GATOR subcomplex GATOR2, MIOS functions within the amino acid-sensing branch of the TORC1 signaling pathway. It indirectly activates mTORC1 and the TORC1 signaling pathway through inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
[UniProt: Q9NXC5-1]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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