Thermo Fisher Scientific JAM3 Monoclonal Antibody (1D3)
인간 JAM3 단백질을 인식하는 Mouse IgG2a 단일클론 항체. ELISA 검증 완료. 액상 형태로 제공되며 PBS(pH 7.4) 버퍼에 보존제 무첨가. -20°C 보관, 동결/해동 반복 피해야 함. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D3 |
| Immunogen | JAM3 (NP_116190, 82 a.a. approximately 180 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SNRTPVVQEF ESVELSCIIT DSQTSDPRIE WKKIQDEQTT YVFFDNKIQG DLAGRAEILG KTSLKIWNVT RRDSALYRCE VVARNDRKEI DEIVIELT*
Target Information
JAM3 is involved in tight junctions and represents one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.
The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells.
Unlike other proteins in this family, this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions.
The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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