Thermo Fisher Scientific Cyclin C Polyclonal Antibody
Cyclin C 단백질을 검출하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
- 카탈로그번호
- PA5100706
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CCNC (Accession P24863), corresponding to amino acid residues E249–S283 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850210 |
Product Specific Information
Antibody detects endogenous levels of total Cyclin C.
Target Information
Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae.
Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with CDK8, a novel protein kinase of the CDK family.
It is suggested that Cyclin C and CDK8 control RNA polymerase II function. Human CDK8–Cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-100706_Cyclin_C_P24863-1_Rabbit.svg, PA5-100706_Cyclin_C_P24863-1_Rabbit_PDP.jpeg)
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