Thermo Fisher Scientific CYP1A2 Monoclonal Antibody (OTI2E9), TrueMAB
CYP1A2 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 유세포분석에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 PBS/BSA/glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA501197
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E9 |
| Immunogen | Full-length human recombinant CYP1A2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
The CYP1A2 protein localizes to the endoplasmic reticulum and its expression is induced by polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke.
Although the enzyme’s endogenous substrate is unknown, it can metabolize certain PAHs to carcinogenic intermediates. Other xenobiotic substrates include caffeine, aflatoxin B1, and acetaminophen.
The transcript of this gene contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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