Thermo Fisher Scientific Ankyrin G Polyclonal Antibody

Thermo Fisher Scientific Ankyrin G Polyclonal Antibody

Product Specifications

Product Specific Information

Immunogen sequence:
ENNVFHDPVD GWQNETSSGN LESCAQARRV TGGLLDRLDD SPDQCRDSIT SYLKGEAGKF EANGSHTEIT PEAKTKSYFP ESQNDVGKQ

Target Information

Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms localized to axon initial segments and nodes of Ranvier.
Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells.
Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain.
Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.