Thermo Fisher Scientific UMPS Polyclonal Antibody
UMPS 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 비결합 항체. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UMPS (Recombinant protein control fragment: Product #RP-96306) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2649262 |
Product Specific Information
Immunogen sequence:
RLLSQVADIL FQTAQNAGIS FDTVCGVPYT ALPLATVICS TNQIPMLIRR KETKDYGTKR LVEGTINPGE TCLIIEDVVT SGSSVL
Sequence Identity:
- Mouse: 91%
- Rat: 91%
Target Information
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway.
- The N-terminal enzyme (orotate phosphoribosyltransferase) converts orotic acid to orotidine-5'-monophosphate.
- The C-terminal enzyme (OMP decarboxylase) converts orotidine-5'-monophosphate to uridine monophosphate.
Defects in this gene cause hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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