Thermo Fisher Scientific SUV420H2 Polyclonal Antibody
Western blot 및 유세포분석에 적합한 Rabbit Polyclonal 항체. Human 및 Mouse 반응성. SUV420H2 단백질의 195-220 아미노산 영역을 면역원으로 제작. 액상 형태, 2 mg/mL 농도, PBS 버퍼 및 sodium azide 포함. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 195–220 amino acids of human SUV4-20H2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2196743 |
Product Specific Information
This antibody is predicted to react with rat based on sequence homology.
Target Information
SUV420H2 is a histone methyltransferase that specifically trimethylates Lys-20 of histone H4. H4 Lys-20 trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1, and RBL2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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