Thermo Fisher Scientific CD44var (v3) Monoclonal Antibody (VFF-327v3), Biotin, eBioscience
CD44var (v3) 단백질을 특이적으로 인식하는 Mouse IgG1 단일클론 항체로, Biotin으로 결합되어 있음. Flow Cytometry에 적합하며 인간 시료 반응성. 친화 크로마토그래피로 정제되어 높은 순도와 안정성 제공. 연구용으로만 사용 가능.
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Applications
- Tested Application: Flow Cytometry
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VFF-327v3 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 10 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10597003 |
Additional Formats
Product Specific Information
This antibody specifically recognizes an epitope encoded by exon v3 on the variant portion of human CD44.
Standard CD44 (CD44s) lacks the entire variable region and is mainly found in lymphohematopoietic cells.
Multiple isoforms (CD44v1–CD44v11) contain alternatively spliced exons inserted within the extracellular domain.
Applications Tested: Flow Cytometry.
Target Information
CD44 is a 100 kDa cell surface glycoprotein widely expressed on human leukocytes, white matter of the brain, and certain epithelial cells of the intestine and breast.
Several isoforms exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 acts as a receptor for hyaluronic acid (HA) and plays a role in cell-cell interactions, adhesion, and migration.
It is involved in lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in some carcinomas, potentially related to metastatic potential.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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