Thermo Fisher Scientific BAG3 Polyclonal Antibody
BAG3 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 실험에 적합. E.coli 유래 재조합 단백질을 면역원으로 사용하며, 항원 친화 정제 방식으로 제조됨. 동결건조 형태로 공급되며 PBS/BSA 완충액에 재구성 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human BAG3 recombinant protein (Position: H100–N561) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.01 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745971 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
BAG3 belongs to the BAG family of proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain, promoting substrate release. All BAG proteins share an approximately 45-amino acid BAG domain near the C-terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain both in vitro and in mammalian cells, binding with high affinity and inhibiting its chaperone activity in a Hip-repressible manner.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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