Thermo Fisher Scientific CDK2 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:10,000

Product Specifications

Product Specific Information

Store as concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.

Target Information

CDK2/cyclinO is a member of the cyclin-dependent protein kinase family complexed to CyclinO. CyclinO is a specific protein isoform of the UNG gene localized exclusively in the nucleus and exhibits uracil-DNA glycosylase activity.
CDK2/cyclinO protein levels increase during the G1 phase and are turned over during the cell cycle. Cyclin A–CDK2 levels peak at the G1/S transition, with both proteins associated with DNA in the initiation complex during replication.
Rb protein acts as a substrate for CDK2–Cyclin E and/or CDK2–Cyclin A in vivo. CDK2 is activated and localized to the nucleus during late G1-, S-, and G2-phase.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.