Thermo Fisher Scientific HMGB2 Polyclonal Antibody, MaxPab
HMGB2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, PBS(pH 7.4) 용액 형태로 제공됩니다. Affinity chromatography로 정제되었으며, 보존제가 포함되어 있지 않습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HMGB2 (NP_002120.1, 1 a.a. – approximately 209 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MGKGDPNKPR GKMSSYAFFV QTCREEHKKK HPDSSVNFAE FSKKCSERWK TMSAKEKSKF
EDMAKSDKAR YDREMKNYVP PKGDKKGKKK DPNAPKRPPS AFFLFCSEHR PKIKSEHPGL
SIGDTAKKLG EMWSEQSAKD KQPYEQKAAK LKEKYEKDIA AYRAKGKSEA GKKGPGRPTG
SKKKNEPEDE EEEEEEEDED EEEEDEDEE
Target Information
HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family.
These proteins are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells.
In vitro studies have shown that HMGB2 efficiently bends DNA and forms DNA circles, suggesting a role in promoting DNA flexibility and facilitating cooperative interactions between cis-acting proteins.
It is also implicated in DNA double-strand break repair and V(D)J recombination processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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