Thermo Fisher Scientific HLA-G Monoclonal Antibody (1D6)
인간 HLA-G 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot 및 ELISA에 사용 가능. 합성 펩타이드 면역원 기반으로 제작되었으며, PBS 용액 형태로 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1–5 µg/mL
- ELISA: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D6 |
| Immunogen | A synthetic peptide corresponding to human HLA-G (aa 166–188, UniProt ID: P17693-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ISKRKCEAAN VAEQRRAYLE GTC
Target Information
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons.
- Exon 1: Leader peptide
- Exons 2–3: α1 and α2 domains (peptide binding)
- Exon 4: α3 domain
- Exon 5: Transmembrane region
- Exon 6: Cytoplasmic tail
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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