Thermo Fisher Scientific Calcium Channel beta-4 Polyclonal Antibody
Rabbit polyclonal antibody targeting Calcium Channel beta-4 (CACNB4). Validated for Western blot in human, mouse, and rat samples. Affinity purified and supplied as liquid form at 1 mg/mL concentration. Stored in PBS with 50% glycerol and 0.02% s...
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CACNB4 (Accession O00305), corresponding to amino acid residues V488–L520 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899341 |
Product Specific Information
Antibody detects endogenous levels of total CACNB4.
Target Information
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
The encoded protein modulates G protein inhibition, increases peak calcium current, controls alpha-1 subunit membrane targeting, and shifts voltage dependence of activation/inactivation.
Mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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