Thermo Fisher Scientific HFE Monoclonal Antibody (1G12)
HFE 단백질을 인식하는 Mouse monoclonal antibody(클론 1G12). Western blot, ICC/IF, ELISA에 사용 가능. Human 시료에 반응하며, Affinity chromatography로 정제됨. PBS(pH 7.4) 용액 형태, 보존제 없음, -20°C 보관.
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- H00003077-M01
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G12 |
| Immunogen | HFE (NP_000401, 115–205 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SHTLQVILGC EMQEDNSTEG YWKYGYDGQD HLEFCPDTLD WRAAEPRAWP TKLEWERHKI RARQNRAYLE RDCPAQLQQL LELGRGVLDQ Q
Target Information
The protein encoded by this gene is a membrane protein similar to MHC class I-type proteins and associates with beta2-microglobulin. It is thought to regulate iron absorption by controlling the interaction between the transferrin receptor and transferrin.
Mutations in this gene cause hereditary haemochromatosis, a recessive iron storage disorder. At least nine alternatively spliced variants have been described, with additional variants of undetermined full-length sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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