Thermo Fisher Scientific CFHR1 Monoclonal Antibody (4D7)
CFHR1 단백질을 인식하는 Mouse IgG2b 단클론 항체로 ELISA에 적합합니다. Human 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS(pH 7.4) 완충액에 보존되며 방부제는 포함하지 않습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D7 |
| Immunogen | CFHR1 (AAH16755.1, 19 a.a. – approximately 330 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
EATFCDFPKI NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS PTPKCLRLCF FPFVENGHSE SSGQTHLEGD TVQIICNTGY RLQNNENNIS CVERGWSTPP KCRSTDTSCV NPPTVQNAHI LSRQMSKYPS GERVRYECRS PYEMFGDEEV MCLNGNWTEP PQCKDSTGKC GPPPPIDNGD ITSFPLSVYA PASSVEYQCQ NLYQLEGNKR ITCRNGQWSE PPKCLHPCVI SREIMENYNI ALRWTAKQKL YLRTGESAEF VCKRGYRLSS RSHTLRTTCW DGKLEYPTCA KR
Target Information
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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