Thermo Fisher Scientific NKp44 Recombinant Rabbit Monoclonal Antibody (JE61-04)
인간, 마우스, 랫트에 반응하는 재조합 토끼 단클론 항체로 NKp44 단백질을 검출합니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도의 Protein A 정제 항체입니다. 안정한 액상 제형으로 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE61-04 |
| Immunogen | Recombinant protein within human NK-p44 aa 1–100/276 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931306 |
Target Information
CD336, also known as NKp44 or NCR2, is a 44-kDa transmembrane glycoprotein of the natural cytotoxicity receptor (NCR) family. It contains an ITIM domain in its cytoplasmic tail and requires association with DAP12 for NK cell activation. Originally identified on IL-2-activated NK cells and subsets of γδ T lymphocytes, CD336 expression has also been observed in IL-3-stimulated plasmacytoid dendritic cells, αβ T cells in the small intestinal epithelium, and T cells in cord blood. CD336 plays a key role in the innate immune response of activated NK cells against viral infection and tumor proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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