Thermo Fisher Scientific RD1 Polyclonal Antibody
다중 종 반응성을 가진 Thermo Fisher Scientific의 RD1 Polyclonal Antibody는 Human, Mouse, Rat, Zebrafish 시료에 사용 가능합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human IFRD1, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tis7, also known as IFRD1, is a 442 amino acid membrane-associated, non-nuclear intracellular protein belonging to the IFRD family. It functions as a regulatory protein expressed in various tissues and plays a key role in gene activity regulation during proliferative and differentiative pathways induced by NGF. Reports indicate that Tis7 may act as an autocrine factor modulating ligand-induced signals and promoting the production of differentiated enterocytes. It also acts as a negative regulator of transcriptional activity, repressing genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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