Thermo Fisher Scientific AgRP Polyclonal Antibody
AgRP 단백질을 인식하는 Thermo Fisher Scientific의 산양 유래 폴리클로날 항체로, Western blot과 IHC(파라핀 절편)에 적합합니다. 고순도 항원 친화 크로마토그래피 정제 제품이며, 인간 AgRP에 반응하고 약 40%의 생쥐 AgRP 교차반응을 보입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA547895
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
- Publications: [Reference not provided]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–15 µg/mL
- Publications: [Reference not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf21-derived recombinant human AgRP/ART (Ala21–Thr132) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610536 |
Product Specific Information
- In Western blots, approximately 40% cross-reactivity with recombinant mouse AgRP/ART is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Agouti-related protein (AgRP), also known as agouti-related peptide, is a neuropeptide produced in the brain by AgRP/NPY neurons.
In humans, the AGRP gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptors.
AgRP regulates hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, contributing to weight homeostasis.
Mutations in this gene have been associated with late-onset obesity.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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