Thermo Fisher Scientific AFF4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AFF4. Recombinant protein control fragment (Product #RP-89295). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AFF4,uniProtId:Q9UHB7-1,ncbiNodeId:9606,antigenRange:509-640,antigenLength:1163,antigenImageFileName:PA5-54866_AFF4_Q9UHB7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54866_AFF4_Q9UHB7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637745

Product Specific Information

Immunogen sequence: QGTGNSYTDT SGPKETSSAT PGRDSKTIQK GSESGRGRQK SPAQSDSTTQ RRTVGKKQPK KAEKAAAEEP RGGLKIESET PVDLASSMPS SRHKAATKGS RKPNIKKESK SSPRPTAEKK KYKSTSKSSQ KS

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

Target Information

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.