Thermo Fisher Scientific AFF4 Polyclonal Antibody
Human AFF4 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P) 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 저장용액에 40% 글리세롤 포함, 4°C 또는 -20°C 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AFF4. Recombinant protein control fragment (Product #RP-89295) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637745 |
Product Specific Information
Immunogen sequence:
QGTGNSYTDT SGPKETSSAT PGRDSKTIQK GSESGRGRQK SPAQSDSTTQ RRTVGKKQPK KAEKAAAEEP RGGLKIESET PVDLASSMPS SRHKAATKGS RKPNIKKESK SSPRPTAEKK KYKSTSKSSQ KS
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 91%
Target Information
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia.
It is a component of the positive transcription elongation factor b (P-TEFb) complex.
A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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