Thermo Fisher Scientific PEN2 Polyclonal Antibody
PEN2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 다양한 종에서 반응하며 Western blot에 적합. 0.5 mg/mL 농도의 액상 형태로 제공되며 Protein A로 정제. Presenilin enhancer protein 2 연구용으로 사용.
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- pk
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Applications
- Western Blot (WB): 3–7 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Human, Marsupial, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acid 1–50 of human Presenilin enhancer protein 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540947 |
Target Information
Presenilins are components of the gamma-secretase protein complex, required for intramembranous processing of type I transmembrane proteins such as Notch and beta-amyloid precursor protein. Notch signaling mediates various developmental cell fates. Processing of beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer’s disease. PEN2 protein is essential for Notch pathway signaling and gamma-secretase activity and accumulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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