Thermo Fisher Scientific LRRFIP1 Polyclonal Antibody
Human 및 Mouse 반응성을 가지는 Rabbit Polyclonal 항체로, LRRFIP1 단백질(aa 200–250)을 인식합니다. Western blot에 2–5 µg/mL 농도로 사용 가능하며, Protein A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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- PA523445
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Applications
Western Blot (WB)
- Tested Dilution: 2–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acid 200–250 of human LRRFIP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540945 |
Target Information
Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein that mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. It also binds the TNF- -308 promoter polymorphism site, suggesting a role in TNF- production regulation. FLAP-1, LRRFIP2, and FLIIH coordinate inflammatory responses after infection and may serve as novel targets for controlling TLR-mediated inflammatory and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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