Thermo Fisher Scientific Pan-cadherin Monoclonal Antibody (GT2610)
인간 반응성 Pan-cadherin 단백질을 인식하는 Mouse IgG1 단일클론 항체입니다. Western blot에 최적화되어 있으며, CDH1~CDH4 등 다양한 cadherin 단백질 검출에 사용됩니다. Protein G로 정제된 액상 형태로 제공되며, 연구용으로 적합합니다.
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Thermo Fisher Scientific Pan-cadherin Monoclonal Antibody (GT2610)
Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT2610 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human cadherin (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735301 |
Product Specific Information
- Positive Control: IMR32, SK-N-AS, MCF-7
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Pan Cadherin (including CDH1, CDH2, CDH3, CDH4) proteins are transmembrane molecules mediating calcium-dependent intercellular adhesion.
Cadherins regulate morphogenetic movements during development and control cell surface adhesion via homotypic binding.
N-cadherin function depends on actin-cytoskeleton association through interactions with cytoplasmic catenin proteins.
This classical cadherin is a calcium-dependent cell-cell adhesion glycoprotein with five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail.
It functions during gastrulation and contributes to left-right asymmetry establishment.
In the CNS, it mediates presynaptic to postsynaptic adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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