Thermo Fisher Scientific MAGE1 Monoclonal Antibody (MA454)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-1.0 µg/mL

-

Immunohistochemistry (IHC)

-

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:12.5-1:25

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

MA454

Immunogen

Partially purified, full length recombinant human MAGE-1 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAGE1,uniProtId:P43355-1,ncbiNodeId:9606,antigenRange:1-309,antigenLength:309,antigenImageFileName:MA5-11338_MAGE1_P43355-1_House_mouse.svg,antigenImageFileNamePDP:MA5-11338_MAGE1_P43355-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10981544

Product Specific Information

MA5-11338 targets MAGE-1 in IF, IHC (P), and WB applications and shows reactivity with Canine, Human, and Rat samples.

The MA5-11338 immunogen is partially purified, full length recombinant human MAGE-1 protein.

Target Information

Human malignant neoplasms carry rejection antigens that are recognized by the patients` autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.