Thermo Fisher Scientific Protein C (Active) Monoclonal Antibody (PC107)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

-

Inhibition Assays (IA)

1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

PC107

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

100 µg/mL

Purification

Protein G

Storage buffer

PBS with 0.1% BSA

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_3091126

Product Specific Information

The monoclonal antibody PC107 is specific for activated human protein C (APC) and it lacks reactivity for Protein C. The monoclonal antibody recognizes the light chain of the APC molecule.

Target Information

Protein C is a protein that plays a crucial role in the regulation of blood clotting. It is a vitamin K-dependent serine protease that is activated by thrombin, a protein that promotes blood clotting. Once activated, protein C proteolytically cleaves and inactivates factors V and VIII, which are essential for the formation of blood clots. This process helps to prevent excessive blood clotting and maintain the normal flow of blood through the body. In addition to its anticoagulant function, protein C has also been shown to have anti-inflammatory and cytoprotective properties, suggesting that it may have a broader role in maintaining vascular health.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.